Detalhe da pesquisa
1.
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
; 184(18): 4784-4818.e17, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450027
2.
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.
Cell
; 184(24): 6003-6005, 2021 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34822786
3.
A functional genomics approach reveals suggestive quantitative trait loci associated with combined TLR4 and BCP crystal-induced inflammation and osteoarthritis.
Osteoarthritis Cartilage
; 31(8): 1022-1034, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37105395
4.
Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression.
Rheumatology (Oxford)
; 62(3): 1286-1295, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924962
5.
WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion.
Cell Mol Life Sci
; 79(2): 82, 2022 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35048158
6.
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Am J Hum Genet
; 102(1): 88-102, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29304378
7.
Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis.
Ann Rheum Dis
; 80(5): 598-604, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34412027
8.
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain.
PLoS Genet
; 14(9): e1007601, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30261039
9.
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero.
Hum Mol Genet
; 27(11): 2025-2038, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29659830
10.
Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.
PLoS Genet
; 12(10): e1006260, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27701424
11.
A systematic analysis highlights multiple long non-coding RNAs associated with cardiometabolic disorders.
J Hum Genet
; 63(4): 431-446, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29382920
12.
Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.
Ann Rheum Dis
; 76(12): 2046-2053, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28855172
13.
Defining type 2 diabetes polygenic risk scores through colocalization and network-based clustering of metabolic trait genetic associations.
Genome Med
; 16(1): 10, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38200577
14.
Cohort profile: Worldwide Collaboration on OsteoArthritis prediCtion for the Hip (World COACH) - an international consortium of prospective cohort studies with individual participant data on hip osteoarthritis.
BMJ Open
; 14(4): e077907, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637130
15.
The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.
EBioMedicine
; 95: 104759, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37619450
16.
A Genome-Wide Association Study Meta-Analysis of Alpha Angle Suggests Cam-Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults.
Arthritis Rheumatol
; 75(6): 900-909, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36662418
17.
Risk Assessment for Hip and Knee Osteoarthritis Using Polygenic Risk Scores.
Arthritis Rheumatol
; 74(9): 1488-1496, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35644035
18.
Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.
Int J Epidemiol
; 51(4): 1254-1267, 2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34897459
19.
Diversity, compositional and functional differences between gut microbiota of children and adults.
Sci Rep
; 10(1): 1040, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31974429
20.
Role of Epigenomics in Bone and Cartilage Disease.
J Bone Miner Res
; 34(2): 215-230, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715766